In his latest notes column, FanRag’s Jon Heyman reports that while teams such as the Astros, Pirates, Rangers and Yankees were all linked to Jose Quintana in trade rumors this offseason, the best offer the White Sox received came from an unnamed club that is currently perceived as more of a rebuilding team. That could mean any number of teams — the Braves, Phillies, Twins, Reds, Brewers and Padres are all in the midst of retooling their organizations — and further context is seemingly unknown at this time. A trade of Quintana, at this point, seems far likelier to occur this summer than during the final days of Spring Training, though Heyman’s note is a reminder that Quintana would appeal to virtually any club in baseball. With four years and $ remaining on his contract, Quintana’s affordable level of excellence can help clubs looking to win now or those looking to contend more in 2018-19.
A number of synchronization methods for goats have been evaluated under research conditions. The most widely used method in the doe is the treatment of progesterone or progestagen for 9-11 days followed by a luteolytic dose of prostaglandin (or an analogue) administered in the period 36-48h prior to removal of intravaginal sponge (Baldassarre and Karatzas, 2004). The progesterone or progestagen treatment can be delivered through an intravaginal sponge, a Controlled Internal Drug Release (CIDR) device or a subcutaneous implant (Evans and Maxwell, 1987; Ritar et al. , 1989; Freitas et al. , 1997). Although sponges are widely used either in conjunction with Pregnant Mare Serum Gonadotrophin (PMSG), FSH or prostaglandin to more tightly synchronize and/or induce a superovulatory response, but sponges are not preferred as these frequently cause discomfort and may adhere to the vaginal wall causing problems with removal (Holtz, 2005). An alternative means of supplying continuous, exogenous progesterone has been the CIDR developed for goats in New Zealand. The CIDR device is constructed from natural progesterone impregnated medical silicone elastomer molded over a nylon core. Currently the CIDR and subcutaneous implants are preferable than sponges because these are easy to use (Holtz, 2005). Ovulation in the does can be synchronized more precisely by administering GnRH around the time of estrus (Pierson et al. , 2003), which improves the success of fixed-time AI and the collection of oocytes or embryos at a controlled stage of development for specific applications such as oocytes for In Vitro Production (IVP), Intracytoplasmic Sperm Injection (ICSI) or Somatic Cell Nuclear Transfer (SCNT) and zygotes for pronuclear microinjection (Baldassarre and Karatzas, 2004). Although, in the past, a considerable attention was focused in estrus synchronization, however, there is an urgent need for additional research conducted in a well-organized and systematic fashion to help establish guidelines for efficient breeding, AI, oocyte or embryo recovery and ET programs. Timeline of significant finding in estrus synchronization of does has been depicted in Table 2 .
Aug 5 - MLB suspended 12 other players for 50 games. They were: Texas Rangers outfielder Nelson Cruz, San Diego Padres shortstop Everth Cabrera, Detroit Tigers shortstop Jhonny Peralta, Philadelphia Phillies reliever Antonio Bastardo, New York Mets outfielder Jordany Valdespin, Yankees catcher Francisco Cervelli, Seattle Mariners catcher Jesus Montero, New York Mets outfield prospect Cesar Puello, San Diego Padres pitching prospect Fautino De Los Santos, Houston Astros pitching prospect Sergio Escalona and New York Yankees outfield prospect Fernando Martinez.