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Taurine is an essential dietary requirement for feline health, since house cats (and all members of the cat family ) cannot synthesize the compound. [70] The absence of taurine causes a cat's retina to slowly degenerate, causing eye problems and (eventually) irreversible blindness – a condition known as central retinal degeneration (CRD), [71] [72] as well as hair loss and tooth decay. Decreased plasma taurine concentration has been demonstrated to be associated with feline dilated cardiomyopathy . [73] Unlike CRD, the condition is reversible with supplementation. Taurine is now a requirement of the Association of American Feed Control Officials (AAFCO) and any dry or wet food product labeled approved by the AAFCO should have a minimum of % taurine in dry food and % in wet food. [74] Studies suggest the amino acid should be supplied at 10 mg/kg of bodyweight/day for domestic cats. [75]

In the Oxford Journal of Gerontology Series A: Biological Sciences and Medical Sciences, the popular nonsteroidal SARM LGD 4033 (Ligandrol) has been recently studied for it’s effectiveness and safety in healthy young men. Results were favorable indicated by hormone and lipid levels returning to normal without the use of a post cycle therapy. No dangers were detected throughout the study. although there was noticeable suppression in testosterone and HDL cholesterol, it was not significant enough to cause adverse reactions. Because LGD 4033 is considered one of the strongest and most potent nonsteroidal SARMs available, it is not likely that less potent SARMs will produce any harmful effects (Bhasin, 2010).

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It shall be noticed, that in men, approximately 5% of testosterone undergoes 5α-reduction to form the more potent androgen, dihydrotestosterone (DHT), also known as androstanolone. From another side approximately % of testosterone is converted into estradiol (the primary female sex hormone) by aromatase an enzyme expressed in the brain, liver, and adipose tissues. Hence, don`t forget to take precautions to avoid respective side effects. Thereof we recommend to perform blood works and take aromatase inhibitors on cycle (if required, anastrozole preferably) and SERMs (clomifene, toremifene) during post cycle therapy (PCT).

Pharmacokinetically , hydroxyzine is rapidly absorbed and distributed in oral and intramuscular administration, and is metabolized in the liver; the main metabolite (45%), cetirizine , is formed through oxidation of the alcohol moiety to a carboxylic acid by alcohol dehydrogenase , and overall effects are observed within one hour of administration. Higher concentrations are found in the skin than in the plasma. Cetirizine, although less sedating, is non- dialyzable and possesses similar anti-histaminergic properties. The other metabolites identified include a N -dealkylated metabolite, and an O -dealkylated 1/16 metabolite with a plasma half-life of 59 hours. These pathways are mediated principally by CYP3A4 and CYP3A5 . [37] "In animals, hydroxyzine and its metabolites are excreted in feces via biliary elimination." [38]

Rat labs steroids

rat labs steroids

It shall be noticed, that in men, approximately 5% of testosterone undergoes 5α-reduction to form the more potent androgen, dihydrotestosterone (DHT), also known as androstanolone. From another side approximately % of testosterone is converted into estradiol (the primary female sex hormone) by aromatase an enzyme expressed in the brain, liver, and adipose tissues. Hence, don`t forget to take precautions to avoid respective side effects. Thereof we recommend to perform blood works and take aromatase inhibitors on cycle (if required, anastrozole preferably) and SERMs (clomifene, toremifene) during post cycle therapy (PCT).

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