Eight randomized controlled trials including 771 patients (366 in steroid and 405 in comparator groups) were included. There was variability in the studies in the dose of TFE steroids, frequency, and number of procedures. Patients who received TFE steroids reported a significant, but clinically modest, reduction in mean pain scores (0-10 scale) compared with LA/saline (- points; 95% confidence interval, - to - points; P < , I² = 90%; GRADE weak recommendation; moderate-quality evidence) at 3 months after the interventions. TFE steroids did not decrease physical disability at 1 to 3 months after the intervention (GRADE strong recommendation ↓; high-quality evidence) or incidence of surgery at 12 months after the intervention (GRADE strong recommendation ↓; moderate-quality evidence) compared with LA/saline.
I have had a series of both facet block injections and steroid epidurals with my most recent one in August, 2012. I have degenerative disc/spondylolisthesis at L4/5 diagnosed years ago. I am very fit and worked hard most of my life to eat healthy, exercise at an intense level, and keep my weight in normal range. Facet blocks and steroid epidurals will make you gain weight and even though I've continued to exercise and watch my diet throughout my treatments, I have still gained 10-15 lbs.
Some prescriptions like Lyrica will also make you gain wieght very quickly.