A large number of studies are dedicated to dynamic rejuvenation of the motor system following acute events like stroke. Similar insults of motor system can also be noticed in chronic diseases such as MS, with a potential role of rehabilitative approach in improving the quality of life in MS patients. Brain activation is found to be exaggerated in MS patients with normal motor function compared to healthy controls, assessed by means of a finger tapping study [ 20 ]. Brain activation changes with increased diffuse brain injury and increased hand disability was found to be present in active as well as passive finger movements thus mirroring brain reorganization.
Incomitant esotropias are conditions in which the esotropia varies in size with direction of gaze. They can occur in both childhood and adulthood, and arise as a result of neurological, mechanical or myogenic problems. These problems may directly affect the extra-ocular muscles themselves, and may also result from conditions affecting the nerve or blood supply to these muscles or the bony orbital structures surrounding them. Examples of conditions giving rise to an esotropia might include a VIth cranial nerve (or Abducens) palsy, Duane's syndrome or orbital injury.